Tuesday, December 7 HealthDay News)-women with localized breast cancer are less likely that becoming invasive cancer if maintained radiation after the operation, a new study finds.
The researchers also found that the treatment with the drug tamoxifen significantly reduces the risk of repetition of localized cancer.
The three Nations study included patients with ductal carcinoma in situ (DCIS), the most common type of non-invasive breast cancer, were followed for a median of 12.7 years.
The researchers found that radiation after surgery reduces the risk of invasive cancer in the same breast of almost 70 per cent and more than 60% recurring DCIS same chest declined. Radiation therapy did not affect the other breast.
"This study is very important to confirm the benefits of radiation therapy in the treatment of ductal carcinoma in situ and, most importantly, reduce the incidence of invasive cancer development in the same breast,", said Dr. Lauren Cassell, Chief of breast surgery at Lenox Hill Hospital in New York City. "If we could only identify which specific patients were most at risk, we our radiotherapy to those patients target that really benefit from it and to avoid over treating others."
The study also found that treatment with tamoxifen the risk of recurrence of cancer in the same breast reduced by about 30 percent, and it reduces the risk of new cancer in the other breast of more than 65 percent.
The results seem online December 7 in the Lancet Oncology.
The results confirm "The long-term beneficial effects of radiotherapy and reports that handle a benefit to tamoxifen in reducing the local and contralateral new breast events for women with DCIS by complete excision" wrote study author Jack Cuzick, Cancer Research UK, Queen Mary's School of medicine and dentistry in London in a press release by the magazine.
"This study highlights the importance of radiation therapy in high-quality [more rapidly growing and tend to spread] DCIS and proposes a role for tamoxifen, primarily for new contralateral disease" they joined.
More information
The American Cancer Society has more about breast cancer.
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